Susan Smith

Chief Operating Officer Centene

Last Reviewed: October 1, 2026

Executive Summary

Susan Smith has been Centene’s Chief Operating Officer since January 2024, six months after joining the company. She spent the preceding years in senior roles at Humana, where she led Medicare, clinical solutions, and healthcare quality reporting and improvement. Centene ranked No. 19 on the 2026 Fortune 500.

Career Highlights

• Chief Operating Officer of Centene since January 2024.
• Senior Vice President of Clinical Solutions at Humana, 2021 to 2022.
• Senior Vice President of Medicare at Humana, 2019 to 2021.
• Senior Vice President of Healthcare Quality Reporting and Improvement at Humana, 2016 to 2019.

Professional Journey

Smith was Senior Vice President of Healthcare Quality Reporting and Improvement at Humana from 2016, Senior Vice President of Medicare from 2019 and Senior Vice President of Clinical Solutions from 2021, and in late 2022 led Clinical, Quality and Enterprise Solutions.

She joined Centene in June 2023 and became Chief Operating Officer in January 2024.

Education

No first-party source read for this profile states her education.